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What Affects Weight Changes?

Kristine Alonso

Ever wonder why Semaglutide is making waves in weight management?


  • Hormones act as messengers, traveling through the bloodstream, to regulate growth, metabolism, mood, reproduction, and many other functions. They are chemicals in the body

  • Placebo helps distinguist what works best for people. This treatment has technically no effect that is used in research to compare how well a drug or other treatment works.

  • Metabolic Rate This is the rate at which your body uses energy to do basic things such as breathing, regulating your body temperature, and circulating blood. 

  • Type 2 Diabetes This is an acquired condition where a person’s body has become resistant to insulin. A lifestyle change can reverse of improve Type 2 Diabetes and this is done by drastic weight loss, changes in diet and lifestyle shifts.


A person checking weight
Regularly checking weight is important

Factors affecting weight:

  • genetics

  • cultural background

  • medical conditions and disability

  • mental illness – which can affect appetite and motivation to shop and cook healthy food or be active

  • some medicines – which can increase appetite or slow the metabolism

  • eating disorders

  • drugs, tobacco, or/and alcohol

  • where people live, go to school and work

  • the media

  • availability of convenience foods

  • portion sizes

  • time pressures – which can make it hard to cook healthy meals and exercise

  • lifestyle

  • shift work – due to disrupted sleep and eating patterns

  • inadequate sleep – people who sleep less than 6 hours a night are more likely to gain weight


A person eating a salad
Eating a healthy diet can help in weight management
According to the National Institute of Diabetes and Digestive and Kidney Diseases, insulin resistance risk factors include:
  • Weight - Being overweight or obese, especially having excess body fat in the belly and around the organs

  • Age - 45 or older

  • Genetics - Having a parent or sibling with diabetes

  • Ethnicity - African American, Alaska Native, American Indian, Asian American, Hispanic/Latino, Native Hawaiian or Pacific Islander American

  • Physical inactivity

  • Health conditions High blood pressure and abnormal cholesterol levels, heart disease

  • History of gestational diabetes



Sources: Bergmann NC, Davies MJ, Lingvay I, Knop FK. Semaglutide for the treatment of overweight and obesity: A review. Diabetes Obesity Metabolism. 2023;25(1):18-35. doi:10.1111/dom.14863


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